Small fiber degeneration in post-stroke complex regional pain syndrome I

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Evidence of focal small-fiber axonal degeneration in complex regional pain syndrome-I (reflex sympathetic dystrophy).

CRPS-I consists of post-traumatic limb pain and autonomic abnormalities that continue despite apparent healing of inciting injuries. The cause of symptoms is unknown and objective findings are few, making diagnosis and treatment controversial, and research difficult. We tested the hypotheses that CRPS-I is caused by persistent minimal distal nerve injury (MDNI), specifically distal degeneration...

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Long-term Prednisolone in Post-stroke Complex Regional Pain Syndrome.

BACKGROUND There is no study on the long-term use of prednisolone in post-stroke complex regional pain syndrome-1 (CRPS1). OBJECTIVE To evaluate the efficacy and safety of long-term low dose prednisolone in post-stroke CRPS-I. STUDY DESIGN Open-labeled randomized controlled trial. SETTING Tertiary care teaching institute. METHODS Seventy-seven out of 396 (19.4%) patients with stroke had...

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Is reflex sympathetic dystrophy/complex regional pain syndrome type I a small-fiber neuropathy?

Neurologist S. Weir Mitchell first described "causalgia" following wartime nerve injury, with its persistent distal limb burning pain, swelling, and abnormal skin color, temperature, and sweating. Similar post-traumatic symptoms were later identified in patients without overt nerve injuries after trauma. This was labeled reflex sympathetic dystrophy (RSD; now complex regional pain syndrome type...

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Post-lumbar surgery complex regional pain syndrome.

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Nottingham University Hospitals, Nottingham, United Kingdom, 2 Blond McIndoe Laboratories, Division of Cell Matrix Biology and Regenerative Medicine, Faculty of Biology Medicine and Health, Manchester Academic Health Science Centre, School of Biological Sciences, University of Manchester, Manchester, United Kingdom, Department of Plastic Surgery & Burns, Manchester Academic Health Science Centr...

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ژورنال

عنوان ژورنال: Neurology

سال: 2007

ISSN: 0028-3878,1526-632X

DOI: 10.1212/01.wnl.0000266967.38657.3a